Research and scientific publications

van Oomen-Nijhof A, Jacobse JN, Steggink LC, Lefrandt JD, Gietema JA, Van Leeuwen FE, Schaapveld M, Sonke GS.

Adjuvant aromatase inhibitor therapy and early markers for cardiovascular disease in breast cancer survivors.

Breast Cancer Res Treat. 2022 Dec;196(3):591-602. doi:10.1007/s10549-022-06714-0. Epub 2022 Oct 01. PMID: 36181605. Observational Study

Steggink LC.

Langetermijneffecten van behandelingen van borstkanker en zaadbalkanker.

Ned Tijdschr Oncol.. 2022 Aug;19(5):202-204. URI: https://www.ntvo.nl/journal-article/langetermijneffecten-van-behandelingen-van-borstkanker-en-zaadbalkanker/. News

de Boo L, Quist J, Opdam M, Jozwiak K, Gazinska P, Peters D, Horlings HM, Steenbruggen TG, Steggink LC, de Vries EGE, Sonke GS, Gietema JA, Tutt A, Kok M, Grigoriadis A, Linn SC.

Predictive value of ectopic HORMAD1 tumor expression for high-dose platinum-based chemotherapy benefit in patients with high-risk HER2-negative breast cancer.

J Clin Oncol. 2022 Jun 2;40(16suppl; abstr 541). doi:10.1200/JCO.2022.40.16_suppl.541.
Abstract at 2022 American Association of Clinical Oncology Annual Meeting; 2022 Jun 6; Chicago, USA. Abstract 541. Meeting Abstracts

Naaktgeboren WR, Groen WG, Jacobse JN, Steggink LC, Walenkamp AME, Van Harten WH, Stuiver MM, Aaronson NK, Aleman BMP, Van der Meer P, Schaapveld M, Sonke GS, Gietema JA, Van Leeuwen FE, May AM.

Physical activity and cardiac function in long-term breast cancer survivors.

J Am Coll Cardiol CardioOnc. 2022 Jun;4(2):183-191. doi:10.1016/j.jaccao.2022.02.007. Epub 2022 Apr 19. PMID: 35818555. Observational Study

Steggink LC.

Long-term outcome and treatment-related toxicity in patients with breast and testicular cancer.

[Groningen]: University of Groningen, 2022. 198 p. doi:10.33612/diss.201214971. Download PDF Academic Dissertation

Steggink LC, Boer H, Meijer C, Lefrandt JD, Terstappen LWMM, Fehrmann RSN, Gietema JA.

Genome-wide association study of cardiovascular disease in testicular cancer patients treated with platinum-based chemotherapy.

Pharmacogenomics J. 2021 Apr;21(2):152-164. doi:10.1038/s41397-020-00191-8. Epub 2020 Oct 3. PMID: 33011741. Observational Study

Stelwagen J, Lubberts S, Steggink LC, Steursma G, Kruyt LM, Donkerbroek JW, van Roon AM, van Gessel AI, van de Zande SC, Meijer C, Gräfin zu Eulenburg CH, Oosting SF, Nuver J, Walenkamp AME, de Jong IJ, Lefrandt JD, Gietema JA.

Vascular aging in long-term survivors of testicular cancer more than 20 years after treatment with cisplatin-based chemotherapy.

Br J Cancer. 2020 Nov 24;123(11):1599-1607. doi:10.1038/s41416-020-01049-3. Epub 2020 Sep 14. PMID: 32921790. Observational Study

Steenbruggen TG, Steggink LC, Sonke GS.

High-dose chemotherapy with hematopoietic stem cell transplant in patients with high-risk breast cancer - reply.

JAMA Oncol. 2020 Aug 1;6(8):1300-1300. doi:10.1001/jamaoncol.2020.1649. PMID: 32496508. Comment

Steenbruggen TG^*, Steggink LC^*, Seynaeve CM, van der Hoeven JJM, Hooning MJ, Jager A, Konings IR, Kroep JR, Smit WM, Tjan-Heijnen VCG, van der Wall E, Bins AD, Linn SC, Schaapveld M, Jacobse JN, van Leeuwen FE, Schröder CP, van Tinteren H, de Vries EGE, Sonke GS^†, Gietema JA^†.

High-dose chemotherapy with hematopoietic stem cell transplant in patients with high-risk breast cancer and 4 or more involved axillary lymph nodes: 20-year follow-up of a phase 3 randomized clinical trial.

JAMA Oncol. 2020 Apr;6(4):528-534. doi:10.1001/jamaoncol.2019.6276. PMID: 31999296. Randomized Controlled Trial

Jacobse JN^*, Steggink LC^*, Sonke GS, Schaapveld M, Hummel YM, Steenbruggen TG, Lefrandt JD, Nuver J, Crijns APG, Aleman BMP, van der Meer P, Gietema JA^†, van Leeuwen FE^†.

Myocardial dysfunction in long-term breast cancer survivors treated at ages 40–50 years.

Eur J Heart Fail. 2020 Feb;22(2):338-346. doi:10.1002/ejhf.1610. Epub 2019 Nov 6. PMID: 31696625. Observational Study

van den Bogaard VAB, van Luijk P, Hummel YM, van der Meer P, Schuit E, Boerman LM, Maass SWMC, Nauta JF, Steggink LC, Gietema JA, de Bock GH, Berendsen AJ, Smit WGJM, Sijtsema NM, Kierkels RGJ, Langendijk JA, Crijns APG, Maduro JH.

Cardiac function after radiation therapy for breast cancer.

Int J Radiat Oncol Biol Phys. 2019 Jun 1;104(2):392-400. doi:10.1016/j.ijrobp.2019.02.003. PMID: 30763659. Observational Study

Steggink LC, van Beek AP, Boer H, Meijer C, Lubberts S, Oosting SF, de Jong IJ, van Ginkel RJ, Lefrandt JD, Gietema JA, Nuver J.

Insulin-like factor 3, luteinizing hormone and testosterone in testicular cancer patients: effects of β-hCG and cancer treatment.

Andrology. 2019 Jul 16;7(4):441-448. doi:10.1111/andr.12581. Epub 2019 Jan 4. PMID: 30609309. Observational Study

Stelwagen J, Lubberts S, Steggink LC, Kruyt LM, Donkerbroek JW, van Roon AM, van Gessel AI, van de Zande SC, Meijer C, Wempe JB, von Eulenberg C, Nuver J, Walenkamp AME, Lefrandt JD, Gietema JA.

Vascular damage and pulmonary function in very long-term survivors of testicular cancer (TC) treated with cisplatin-based chemotherapy.

Ann Oncol. 2018 Oct 1;29(suppl_8). doi:10.1093/annonc/mdy283.120.
Poster presentation by Stelwagen at 2018 European Society for Medical Oncology Congress; 2018 Oct 22; Munich, Germany. Abstract 911P. Meeting Abstracts

Steenbruggen TG^*, Steggink LC^*, Seynaeve CM, van der Hoeven JJM, Hooning MJ, Jager A, Konings IR, Kroep JR, Smit WM, Tjan-Heijnen VCG, van der Wall E, Bins AD, Linn SC, Schaapveld M, van Leeuwen FE, Schroder CP, van Tinteren H, de Vries EGE, Sonke GS^†, Gietema JA^†.

High-dose chemotherapy (HDCT) with hematopoietic stem cell transplantation (HSCT) in high-risk breast cancer (BC) patients with ≥4 involved axillary lymph nodes (ALN): 20-year follow-up of a randomized phase 3 study.

Ann Oncol. 2018 Oct 1;29(suppl_8). doi:10.1093/annonc/mdy270.184.
Proffered (oral) presentation by Steenbruggen at 2018 European Society for Medical Oncology Congress; 2018 Oct 19; Munich, Germany. Abstract 187O. Meeting Abstracts

Lubberts S, Kruyt LM, Steggink LC, Steursma G, Nuver J, Oosting SF, van Ginkel RJ, de Jong IJ, Eulenburg C, Lefrandt JD, Meijer C, Sluiter WJ, Gietema JA.

Life expectancy 20 years after cisplatin-based treatment for testicular cancer (TC).

J Clin Oncol. 2017;35(15suppl; abstr 4550). doi:10.1200/JCO.2017.35.15_suppl.4550.
Poster presentation at 2017 American Association of Clinical Oncology Annual Meeting; 2017 Jun 4; Chicago, USA. Abstract 4550. Meeting Abstracts

Tromp J, Steggink LC, van Veldhuisen DJ, Gietema JA, van der Meer P.

Cardio-oncology: progress in diagnosis and treatment of cardiac dysfunction.

Clin Pharmacol Ther. 2017 Apr 10; 101(4):481-490. doi:10.1002/cpt.614. Epub 2017 Feb 14. PMID: 28073142. Review

Steggink LC, van Dijk BAC, Links TP, Plukker JTM.

Survival in anaplastic thyroid cancer in relation to pre-existing goiter: a population-based study.

Am J Surg. 2015 Jun 7;209(6):1013-1019. doi:10.1016/j.amjsurg.2014.06.027. Epub 2014 Aug 7. PMID: 25242682. Observational Study

Steggink LC, Hettema ME, Delsing CE.

Diagnose in beeld: een vrouw met huidafwijkingen en spierzwakte [A woman with skin abnormalities and muscle weakness].

Ned Tijdschr Geneeskd. 2013 Jan;157(30):A6306. Dutch. PMID: 23890170. Case Reports

Steggink L, van Dijk B, Links T, Plukker JT.

Prognostic factors and survival in anaplastic thyroid cancer: a population-based study in North-East Netherlands.

Ann Surg Oncol. 2013;20:S85–S85.
Poster presentation at 2013 Society of Surgical Oncology Annual Cancer Symposium; 2013 Mar 8; National Harbor, Maryland, USA. Abstract P152. Meeting Abstracts